Serum IL-17 levels are higher in critically ill patients with AKI and associated with worse outcomes.
| Author | |
|---|---|
| Abstract |
:
Interleukin-17 (IL-17) antagonism in rats reduces the severity and progression of AKI. IL-17-producing circulating T helper-17 (TH17) cells is increased in critically ill patients with AKI indicating that this pathway is also activated in humans. We aim to compare serum IL-17A levels in critically ill patients with versus without AKI and to examine their relationship with mortality and major adverse kidney events (MAKE). |
| Year of Publication |
:
2022
|
| Journal |
:
Critical care (London, England)
|
| Volume |
:
26
|
| Issue |
:
1
|
| Number of Pages |
:
107
|
| Date Published |
:
2022
|
| ISSN Number |
:
1364-8535
|
| URL |
:
https://ccforum.biomedcentral.com/articles/10.1186/s13054-022-03976-4
|
| DOI |
:
10.1186/s13054-022-03976-4
|
| Short Title |
:
Crit Care
|
| Download citation |
