BVES regulates c-Myc stability via PP2A and suppresses colitis-induced tumourigenesis.
| Author | |
|---|---|
| Abstract |
:
Blood vessel epicardial substance (BVES) is a tight junction-associated protein that regulates epithelial-mesenchymal states and is underexpressed in epithelial malignancy. However, the functional impact of BVES loss on tumourigenesis is unknown. Here we define the in vivo role of BVES in colitis-associated cancer (CAC), its cellular function and its relevance to patients with IBD. |
| Year of Publication |
:
2017
|
| Journal |
:
Gut
|
| Volume |
:
66
|
| Issue |
:
5
|
| Number of Pages |
:
852-862
|
| ISSN Number |
:
0017-5749
|
| URL |
:
https://gut.bmj.com/lookup/pmidlookup?view=long&pmid=28389570
|
| DOI |
:
10.1136/gutjnl-2015-310255
|
| Short Title |
:
Gut
|
| Download citation |
