Decreased MiR-17 in glioma cells increased cell viability and migration by increasing the expression of Cyclin D1, p-Akt and Akt.
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| Abstract |
:
The activating mutations of micro RNA (miR)-17 have been revealed in tumors such as human non-Hodgkin's lymphoma and T cell leukemia. However, it is unclear about the role of miR-17 in glioma cells. The current study aimed to investigate effects of miR-17 mimics or inhibitor on the viability and migration of rat glioma C6 cells, and explore possible mechanisms. |
| Year of Publication |
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0
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| Journal |
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PloS one
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| Volume |
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13
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| Issue |
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1
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| Number of Pages |
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e0190515
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| Date Published |
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2018
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| URL |
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http://dx.plos.org/10.1371/journal.pone.0190515
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| DOI |
:
10.1371/journal.pone.0190515
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| Short Title |
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PLoS One
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| Download citation |
