Matrix Stiffness: the Conductor of Organ Fibrosis.
| Author | |
|---|---|
| Abstract |
:
Organ fibrosis is a lethal component of scleroderma. The hallmark of scleroderma fibrosis is extensive extracellular matrix (ECM) deposition by activated myofibroblasts, specialized hyper-contractile cells that promote ECM remodeling and matrix stiffening. The purpose of this review is to discuss novel mechanistic insight into myofibroblast activation in scleroderma. |
| Year of Publication |
:
2018
|
| Journal |
:
Current rheumatology reports
|
| Volume |
:
20
|
| Issue |
:
1
|
| Number of Pages |
:
2
|
| Date Published |
:
2018
|
| ISSN Number |
:
1523-3774
|
| URL |
:
https://dx.doi.org/10.1007/s11926-018-0710-z
|
| DOI |
:
10.1007/s11926-018-0710-z
|
| Short Title |
:
Curr Rheumatol Rep
|
| Download citation |
